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Basic Clinical Pharmacokinetics [PDF Download]

Basic Clinical Pharmacokinetics PDF
Author: Michael E. Winter
Publisher: Lippincott Williams & Wilkins
Release Date: 2004
ISBN: 9780781741477
Size: 75.19 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 511
View: 7024

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Designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles, the easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. The text provides an introduction to the principles of monitoring drug therapy for those involved in the interpretation of drug levels in a patient care setting. Part One provides a basic review of pharmacokinetic principles. Part Two explains the clinical applications of these principles. Appendices provide commonly used equations and a glossary of pharmacokinetic terms and abbreviations.

Basic Clinical Pharmacokinetics [PDF Download]

Basic Clinical Pharmacokinetics PDF
Author: Michael E. Winter
Publisher: Applied Therapeutics, Incorporated
Release Date: 1988
ISBN: 9780915486083
Size: 48.89 MB
Format: PDF, ePub, Docs
Category : Pharmacokinetics
Languages : en
Pages : 416
View: 6596

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Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. Part One provides a basic review of pharmacokinetic principles. Extensive explanations, graphic illustrations, and detailed algorithms teach the principles of bioavailability, volume of distribution, clearance, elimination rate constant, and half-life. Part Two explains the clinical applications of these principles. Solutions to problems commonly encountered in the practice setting are discussed for specific drugs. New to this edition are chapters on tricyclic antidepressants and cyclosporine, an expanded chapter on dialysis, and updated information on choosing equations and interpreting plasma drug concentrations.

Winter S Basic Clinical Pharmacokinetics [PDF Download]

Winter s Basic Clinical Pharmacokinetics PDF
Author: Paul Beringer
Publisher: LWW
Release Date: 2017-10-15
ISBN: 9781496346421
Size: 57.66 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 624
View: 6680

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Winter's Basic Clinical Pharmacokinetics helps readers apply pharmacokinetics and therapeutic drug monitoring to patient care. An easy-to-read, case-study format has made this text a favorite among students and clinicians. Divided into two parts, Part I reviews basic pharmacokinetic principles, and Part II illustrates the clinical application of these principles to common problems. Extensive explanations emphasize major concepts and accompany complex equations. Figures help visualize concepts NEW chapters include drug dosing in renal disease, pediatric considerations, and pharmacogenomics, as well as antifungals and expansion of the cytotoxic and immunosuppressant therapies Includes cases that address pediatric considerations and pharmacogenomics Updates include new information on the clinical use of serum drug concentrations New Learning Objectives at the beginning of each chapter highlight the key concepts

Clinical Pharmacokinetics [PDF Download]

Clinical Pharmacokinetics PDF
Author: John E. Murphy
Publisher: ASHP
Release Date: 2011-10-01
ISBN: 9781585283477
Size: 12.57 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 434
View: 768

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In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug dosing in renal disease and creatinine clearance estimation A Distinctively Straightforward Guide is Now Even Better The 5th Edition of Clinical Pharmacokinetics is completely revised and updated, making a handy clinical guide even easier to use than ever. · Reorganized content features two sections: Basic Concepts and Special Populations and Specific Drugs and Drug Classes · Sections on special populations, including Dosing in Overweight and Obese Patients, have been conveniently grouped together · Comprehensive introduction covers means, measurements and monitoring · Also conveniently placed up front” a glossary of pharmacokinetics basics and commonly used equations

Concepts In Clinical Pharmacokinetics [PDF Download]

Concepts in Clinical Pharmacokinetics PDF
Author: Joseph T. DiPiro
Publisher: ASHP
Release Date: 2010
ISBN: 1585282413
Size: 18.36 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 248
View: 297

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Short Description: This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.

Handbook Of Basic Pharmacokinetics Including Clinical Applications [PDF Download]

Handbook of Basic Pharmacokinetics   Including Clinical Applications PDF
Author: Wolfgang A. Ritschel
Publisher: Amer Pharmaceutical Assn
Release Date: 1999
ISBN:
Size: 52.29 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 563
View: 3096

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The classic textbook of principles and techniques for practitioners, researchers, and undergraduate and graduate students involved in various applications of pharmacokinetics. Spanning 38 detailed chapters and an appendix providing pharmacokinetic data profiles on more than 420 drugs, this book includes information that is both current and accurate. Presented in a manner that fosters clinical application, readers will gain an understanding of the more precise equations for determining pharmacokinetic values.

Clinical Pharmacokinetics [PDF Download]

Clinical Pharmacokinetics PDF
Author: Malcolm Rowland
Publisher:
Release Date: 1980
ISBN:
Size: 18.47 MB
Format: PDF, Mobi
Category : Chemotherapy
Languages : en
Pages : 331
View: 2771

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Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of Clinical Pharmacokinetics provides a practical perspective, with these added features considerations of both stereochemistry and the increasing number of polypeptide and protein drugs being developed; the range and number of problems at the end of each chapter has been expanded; a second color added to make the text more user friendly; important equations highlighted by shading.

Basic Pharmacokinetics [PDF Download]

Basic Pharmacokinetics PDF
Author: Mohsen A. Hedaya
Publisher: CRC Press
Release Date: 2007-04-23
ISBN: 1420046721
Size: 79.15 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 328
View: 777

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This volume is a self-instructional computer-assisted medium for active learning. Indeed, the tutorial materials included in the accompanying compact disk have received an award from the American Association of Colleges of Pharmacy for innovation in teaching. This volume and its companion CD are intended for students and practitioners in the health professions who need to comprehend the concepts and principles related to how the body absorbs, distributes, metabolizes, and excretes drugs. "...The author's reliance on active learning, his use of examples illustrating important pharmacokinetic principles, and particularly the thoughtful simulation tools he has developed make this text and its companion CD an extremely effective and enjoyable introduction to the field of pharmacokinetics." From the Foreword, Ronald J. Sawchuk Minneapolis, Minnesota Pharmacokinetics has become an essential component of all the processes involved in drug development, discovery, and preclinical evaluation, as well as with the clinical use of drugs. While this has led to the development of many highly complex techniques, basic pharmacokinetic concepts remain the backbone of all these new developments. Consequently, a thorough understanding of the basic concepts is essential before one can tackle the more involved and applied areas of pharmacokinetics. Basic Pharmacokinetics consists of two parts: textual printed materials and highly interactive computer-based presentations. Together, these provide a useful combination that makes it easy to grasp basic principles. The computer-based information is presented in a self-instructional format, which introduces concepts, utilizing highly interactive graphical presentations and simulations. It visualizes the interplay between the different pharmacokinetic parameters, observing how the change in one or more of these parameters impacts the drug concentration-time profile in the body. Uniquely and carefully designed, the learning modules in the CD closely support and complement the text, providing the learner with an opportunity to reinforce his or her understanding of the principles presented.

Clinical Pharmacokinetics [PDF Download]

Clinical Pharmacokinetics PDF
Author: Soraya Dhillon
Publisher: Pharmaceutical Press
Release Date: 2006
ISBN: 9780853695714
Size: 79.59 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 262
View: 4248

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A practical guide to the use of pharmacokinetic principles in clinical practice. Over 30 clinical cases with self-study questions and answers are presented throughout to bridge the gap between pharmacokinetic concepts and their practical application to individual patients. Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning and dose related adverse effects.

Biopharmaceutics And Clinical Pharmacokinetics [PDF Download]

Biopharmaceutics and Clinical Pharmacokinetics PDF
Author: Notari
Publisher: CRC Press
Release Date: 1986-08-26
ISBN: 9780824775230
Size: 66.19 MB
Format: PDF
Category : Science
Languages : en
Pages : 440
View: 4858

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Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface to the Fourth Edition -- Preface to the Third Edition -- Preface to the Second Edition -- Preface to the First Edition -- Nomenclature -- 1: Introduction -- References -- 2: Rates, Rate Constants, and Order -- I. Order -- II. Rates and Rate Constants -- 3: Active and Passive Transport -- I. Introduction -- II. Passive Transport -- III. Active Transport -- References -- 4: Pharmacokinetics -- I. Introduction -- II. Drug Disposition -- III. Constant-Rate Intravenous Infusion -- IV. Compartmental Models and Their Limitations -- V. Absorption Rate Constants -- References -- 5: Biopharmaccutics -- I. Extravascular Administration -- II. Absorption of Drugs from the Gastrointestinal Tract -- III. Factors Influencing Bioavailability -- IV. Evaluation of the Bioavailability of a Single Drug -- V. Drug Delivery to Prolong Duration -- References -- 6: Dosage Regimens -- I. Introduction -- II. Accumulation During Repetitive Dosing -- III. Adjustment of Dosage Regimen in Renal Failure -- IV. Multiple Dosing of Constant-Rate Intravenous Infusions -- References -- 7: Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy -- I. Introduction -- II. Antimicrobial Agents -- III. Pharmacokinetics of Prodrugs -- IV. Stereoisomers -- References -- 8: Pharmacokinetic Applications in Clinical Practice -- I. Introduction -- II. Pharmacokinetic Drug Interactions -- III. Clinical Pharmacokinetics -- References -- Appendix -- Index